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Source document· March 1, 2026

Jefferies updates its AI Risk Basket

View original at seekingalpha.com
Jefferies updates its AI Risk Basket [Hand pointing at digital warning icon with AI and data interface, representing system warning alert, cybersecurity threat, data error, and artificial intelligence risk.] Saksit Sangtong The Jefferies AI Risk Basket used to identify potential decliners from the impact of AI, is down…
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  • AI summaries reduce research value for Gartner

    80% confidence
  • AI reallocates performance ad spend away from Snap

    80% confidence
  • AI agents bypass OTAs for Expedia Group and Booking Holdings

    80% confidence
  • LLM agents replace RPA for UiPath

    80% confidence
  • AI copilots commoditize ticketing for Atlassian

    80% confidence
  • AI agents bypass listings for Zillow Group

    80% confidence
  • AI automates tax preparation for Intuit

    80% confidence
  • AI fears compress allocator fees for StepStone Group

    80% confidence
  • AI commoditizes email personalization for Klaviyo

    80% confidence
  • AI replicates data and cuts pricing for CoStar Group

    80% confidence
  • AI copilots reduce seat pricing for Workday

    80% confidence
  • The starting point is the sub-industries that could be impacted by various disruption vectors. We then combine this with stock-level returns and run it through a series of pre-trained prompts to obtain the stock-specific potential risk and disruption vector

    80% confidence
  • AI automates delivery labor for EPAM Systems

    80% confidence
  • AI fears compress private equity fees and multiples for alternative asset managers

    80% confidence
  • Ironically, we use an AI-assisted search algorithm to identify our AI-risk basket

    80% confidence
  • AI agents bypass CRM workflows for Salesforce

    80% confidence
  • AI content lowers switching costs for Unity Software

    80% confidence
  • Generative tools commoditize design for Adobe

    80% confidence

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Q4 2026 Biotech Catalyst Cluster: Late-Stage Data and PDUFA Dates Converge
Early-to-mid November 2026 is a dense run of clinical readouts and Q3 earnings at AHA, AASLD, ACR and ASH. Mid-cap biotechs (Vir, Mineralys, Arrowhead, Oryzon, Novartis, J&J) are reporting data that feeds into regulatory decisions. The next ones are the ivonescimab BLA (Nov 14) and the lorundrostat PDUFA (Dec 22), followed by ECLIPSE 2/3 and Maritime-1 readouts in Q1 2027. The list also includes an unrelated delisting track (EGM Nov 19, application Jan 25, 2027), and the facts have no AI or fintech content.
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