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Source document· February 20, 2026

Merck vs. Bristol Myers: Which Pharma Stock Is a Better Pick in 2026?

View original at finance.yahoo.com
Merck vs. Bristol Myers: Which Pharma Stock Is a Better Pick in 2026? Merck & Co. MRK and Bristol Myers Squibb BMY are major global drugmakers with expansive, diversified portfolios…
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  • Achieved approximately $1 billion in savings in 2025

    80% confidence
  • Operating expenses expected to decline in 2026, supporting margin expansion

    80% confidence
  • Zacks Consensus Estimate for BMY's 2026 EPS suggests increase of 0.33%

    80% confidence
  • Zacks Consensus Estimate for BMY's 2026 sales implies year-over-year decrease of 2.32%

    80% confidence
  • Expects headwind of approximately $2.5 billion from generic competition in 2026

    80% confidence
  • Zacks Consensus Estimate for MRK's 2026 sales implies year-over-year increase of 2.59%

    80% confidence
  • Keytruda targets peak sales of $35 billion by 2028

    80% confidence
  • Phase III pipeline has almost tripled since 2021

    80% confidence
  • Keytruda will lose patient exclusivity in 2028

    80% confidence
  • Annual revenue guidance of $46.0-$47.5 billion for 2026

    80% confidence
  • BMY's relatively attractive valuation and more favorable 2026 outlook position it as the more compelling investment choice versus MRK at present

    80% confidence
  • Zacks Consensus Estimate for MRK's 2026 EPS suggests decline of 38.75%

    80% confidence
  • Legacy Portfolio sales expected to decline 12-16% in 2026

    80% confidence
  • Expects over $70 billion of potential non-risk-adjusted commercial opportunity for the current pipeline by the mid-2030s

    80% confidence
  • Positioned to launch around 20 drugs over the next few years, with many having blockbuster potential

    80% confidence
  • Targeting $2 billion in annualized cost savings by the end of 2027

    80% confidence
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Q4 2026 Biotech Catalyst Cluster: Late-Stage Data and PDUFA Dates Converge
Early-to-mid November 2026 is a dense run of clinical readouts and Q3 earnings at AHA, AASLD, ACR and ASH. Mid-cap biotechs (Vir, Mineralys, Arrowhead, Oryzon, Novartis, J&J) are reporting data that feeds into regulatory decisions. The next ones are the ivonescimab BLA (Nov 14) and the lorundrostat PDUFA (Dec 22), followed by ECLIPSE 2/3 and Maritime-1 readouts in Q1 2027. The list also includes an unrelated delisting track (EGM Nov 19, application Jan 25, 2027), and the facts have no AI or fintech content.
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