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Source document· December 5, 2025

CoinEx Research November 2025 Report: Painvember's Brutal Reality Check

View original at globenewswire.com
CoinEx Research November 2025 Report: Painvember's Brutal Reality Check HONG KONG, Dec. 05, 2025 (GLOBE NEWSWIRE) -- CoinEx Research’s November 2025 Report: Painvember is a brutal reality check after Uptober’s euphoric highs…
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  • As crypto becomes increasingly institutionalized, macroeconomic factors will play an outsized role in dictating price action

    80% confidence
  • Bitcoin must defend the critical $80,000-$82,000 support zone to avert a deeper bear phase

    80% confidence
  • kimi-k2-thinking marks an intensification of global open-source AI model competition and provides decentralized AI community with new low-cost, high-efficiency model option

    80% confidence
  • Betmoar's volume dominance highlights an 'extreme head effect' driven by superior UX or specific incentives

    80% confidence
  • Long-tail Polymarket front-ends are critical to overall censorship resistance and global market penetration

    80% confidence
  • BTC is highly likely to retest the $80k zone, and a break below could lead to decline toward $73k

    80% confidence
  • Prediction market has successfully transitioned from 'event-driven' model to phase of 'normalized high liquidity'

    80% confidence
  • The monopolistic structure of AI infrastructure might be loosening

    80% confidence
  • Bear case: if stablecoin flows shift to significant outflows, could signal bear market lasting at least 6 months similar to April 2022

    80% confidence
  • ZEC's current cycle may not yet be over as it is driven by fundamentals and spot demand

    80% confidence
  • Bull case: if stablecoin inflows maintain slight growth, current adjustment could end within a quarter similar to May 2024

    80% confidence
  • Next period's stablecoin data is extremely critical and could determine if crypto enters short-term correction or 6+ month bear cycle

    80% confidence
  • November 2025 (Painvember) is a brutal reality check after October's euphoric highs

    80% confidence

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Q4 2026 Biotech Catalyst Cluster: Late-Stage Data and PDUFA Dates Converge
Early-to-mid November 2026 is a dense run of clinical readouts and Q3 earnings at AHA, AASLD, ACR and ASH. Mid-cap biotechs (Vir, Mineralys, Arrowhead, Oryzon, Novartis, J&J) are reporting data that feeds into regulatory decisions. The next ones are the ivonescimab BLA (Nov 14) and the lorundrostat PDUFA (Dec 22), followed by ECLIPSE 2/3 and Maritime-1 readouts in Q1 2027. The list also includes an unrelated delisting track (EGM Nov 19, application Jan 25, 2027), and the facts have no AI or fintech content.
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Satellite-Terrestrial Network Integration Acceleration
Increased investment and launches in hybrid satellite-cellular networks across telecom industry; competitive responses from other carriers; regulatory activity around satellite spectrum; expansion of emergency/rural connectivity use cases
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